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==== TIMESTAMPS: 0:00 Intro 2:10 Our Epidemic of Loneliness 6:11 Leveraging the Creative Arts for Healing 12:21 Evaluating Loneliness in Studies 16:31 How Loneliness Equates to Heightened Disease Risk 19:43 The Loneliness Spiral 21:56 Inflammation 24:38 How World Events Impact Well-Being 26:45 What You Can Do: Art as a Medium for Healing 31:05 How Psychedelics Overlap with Creativity 35:44 Cultural Norms Impact Loneliness 38:31 The Biggest Challenge for Moving Forward 40:57 The Potential of Awe and Nature-Connection 44:24 Correlation Between Loneliness and FMRI Imaging 50:00 Conclusion ==== JEREMY NOBEL, M.D., MPH, is a primary-care physician, public health practitioner, and award-winning poet with faculty appointments at the Harvard T.H

In addition to its work as an antioxidant, glutathione may support the mitochondria the cells energy producers

When System Xc function is impaired or SLC7A11 expression decreases, GSH synthesis becomes limited, and GPX4 activity can no longer be sustained, ultimately exacerbating ferroptosis (83)

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